(This may already be a reported issue -- if so sorry -- but this post might help someone.) I've noticed for a few months that my Logitech VX wireless mouse often requires clicking on something more than once to get an action. And sometimes the cursor doesn't seem to bring the target into full focus when hovering. It's been quite a nuisance. After uninstalling drivers, replacing batteries, and other troubleshooting, I found some references to 2.4MHz interference that could be a cause. One solution was to bring the mouse USB receiver from the back of the computer to the front. But I realized that the condition probably started about the time I installed my Asus RT-N66R (and, duh, it's been sitting handy next to my monitor so I could easily play with it, changing firmware and such, instead of being put up higher where my former router was). The N66 radio has pretty effective coverage, which is why we like it. So it stands to reason that it can also mess with the wireless mouse control if it's too close or the frequencies conflict. To confirm that the router was causing the mouse interference, I shut off both radios in the UI. Voila! -- The mouse worked perfectly. When I turned them back on, so far, still no mouse problems. I haven't checked, but maybe the router sensed the mouse frequency and changed the channel (would it do that?). Naturally, I think the long-term solution is moving the router further from the mouse-receiver proximity. Hope this helps someone else who might be experiencing this problem.