You need to be running Merlin firmware. You need to install Entware then the ntfs-3g driver. Then you likely will discover it does not work as your hard drive is too big.
As I read it the max drive size for the AC3100 is 4 TB. You can get around this by partitioning the drive into smaller than 4 TB segments. Then it should work as long as it is in a case that is externally powered. Making sure your firmware is up to date might also help.
If you have a lot of data to store we strongly recommend using a NAS. A router does not make a good place to store a lot of data. Several companies make single drive NAS that work really well. You can also use a Raspberry Pi to make a NAS you can use with the USB drive.