This was somewhat of a loaded question
At the office, we did a small study to evaluate this very problem in the enterprise space - prior to 11ac, we had a very well designed 11n network, but with AP's that were end-of-life, and approaching end-of-support, so it was time to review options. Knowing that we had the reuse limitations, we knew that multi-channel was going to be an issue, so we set up enterprise class AP's (vendors "A", as incumbent, and vendor "C" as a possible change). Also should note that these are managed AP's with a dedicated controller.
All AP's have common SSID (two SSID's - CorpWIFI-test, and CorpGUEST-test) on both bands, running narrow channels in 2.4 (11n), and 80Mhz channels in 5GHz (as 11ac). In 20Mhz, F3 reuse pattern (as per "best practices"), and 11ac, F2 reuse initially, and then the F1 reuse test case...
F2 reuse looked good, pretty much as expected - we cannot use the DFS channels as luck would have it, we're in a place where DFS gets kicked quite often, and the attendant drops and timers kick in - so we basically can't use those channels..
So, after discussion with the vendors on the channel issue, they both suggested looking at an F1 scheme for 5Ghz - there wasn't much consensus around the table, but we agreed to run a limited test - using 3 AP's, and a good mix of clients (laptops, handsets, tablets, mix of 11n and 11ac, with a couple of older Cisco 11a cards dropped into the mix).
The results were a bit odd, and some folks were surprised - the AP's started coordinating with each other to ensure that all STA's received appropriate airtime on the channel.
Going back to the bench, and breaking out the test boxes, including some very expensive 802.11 tracetools, we started digging into what was going on - and confirmed that as part of an extended BSS set, there was coordination happening as the BSS, and adjacent BSS nodes, and this was happening at the MAC/PHY layers... in other words, at the chipset level, below the vendors operating system in the AP's...
Surprisingly enough, both vendors performed pretty much the same - both "A" and "C" - so having this info, we did a small trial deployment - two suites on one end of the building, and turned up the debug with real-world users. Suite 1 had Vendor A's gear, Suite 2 Vendor C...
And everything was fine.. we did eventually deploy into the entire building - 5 floors, and alternated into an F2 scheme of sorts - everything on the single floor was deployed as F1, and then we alternated high-low from floor to floor...
FWIW - we did end up sticking with the incumbent vendor, but it was a good change to see what the competition had to offer...