That's a pretty good switch - I have about 25 of them (various models) scattered around the network. However, it does come with IOS, which has a rather steep learning curve if you're not already familiar with that software. Assuming the switch has been wiped to the factory configuration, you'll have basic "dumb switch" functionality without doing anything. You can then selectively enable features (such as jumbo frames, VLANs, etc.) as you need them.
Depending on the 3750G model and what software it is running, the switch may offer web-based configuration. Due to Cisco never providing enough memory in their products, code bloat means that the full web-based setup is only available on more recent models, or older models running out-of-date (and smaller) software.
Most of Cisco's IOS-based switches have very similar configuration commands. It is only when you get into more esoteric things that the differences between models become visible. However, some older Cisco switches ran CatOS, which was very different. As a rule of thumb, if the version number is < 8, you've got CatOS and if it is > 10, you've got IOS.
The current software for the older 3750G models is 12.2(55)SE6, while the newer ones is 12.2(58)SE2 or 15.0(2)SE.
If you have any specific questions regarding configuring the switch, post a reply here and I'll try to help.